IJCRR - 7(20), October, 2015
BIOCHEMICAL COMPOSITION AND IN-VITRO THROMBOLYTIC ACTIVITY OF MELISSA OFFICINALIS GROWING NATURALLY IN KURDISTAN REGION\IRAQ
Author: Lana Yousif Mutalib
The present study was aimed to evaluate different parts of Melissa officinalis plant from biochemical composition and thrombolytic activity.
Methods: Leaf and stem part of Melissa officinalis growing naturally were assessed for total phenolic, total flavonoid and total tannin contents. Both parts were examined for the invitro thrombolytic activity.
Results: Significant greater amount of total phenolic (27.882 ± 0.544 mcg GAE\g DW) , total flavonoid (256.708 ± 1.447 mcg QE\g DW) and total tannin contents (424.266 ± 1.026 mcg GAE\g DW) were expressed by the leaf part (p < 0.01) in comparison to the stem part. A significant thrombolytic activity were expressed by both parts in comparison to the control negative (distilled water) (p value < 0.0001) at all tested concentration rage. Greatest thrombolytic activity were detected at high concentration (1000 mcg\ml) for both parts. Generally the thrombolytic activity exhibited by the leaf part was higher than that of stem part.
Conclusion: From the results of study we concluded that leaf part of Melissa officinalis was richest in phytochemical constituents with moderate thrombolytic activity.
Keywords: Melissa officinalis leaf, Melissa officinalis stem, Thrombolytic activity
Lana Yousif Mutalib. BIOCHEMICAL COMPOSITION AND IN-VITRO THROMBOLYTIC ACTIVITY OF MELISSA OFFICINALIS GROWING NATURALLY IN KURDISTAN REGION\IRAQ International Journal of Current Research and Review. 7(20), October, 17-21
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