IJCRR - 7(21), November, 2015
Pages: 47-52
DIGITAL DERMATOGLYPHICS IN CARCINOMA BREAST
Author: Vaishali Paranjape, Ashwini Kundalkar, P. Vatsala Swamy, Yashwant Kulkarni
Category: Healthcare
[Download PDF]
Abstract:
Carcinoma breast is the second most common cancer amongst Indian women. Environmental factors, abnormal genetic background, mutations, hormones and changing lifestyle along with genes 17q21: BRCA1 and 13q21:BRCA2 have strong impact on in its etiopathogenesis. Dermatoglyphic patterns are determined by multiple genes and has multifactorial inheritance. Patterns are unique for every individual, remain unaltered throughout life, easy to record and can be studied by non invasive techniques.
Methods: Digital dermatoglyphics of 100 histopathologically proven cases of Carcinoma breast were recorded, classified and compared with dermatoglypic patterns of 100 subjects not suffering from any clinically obvious genetic disease.
Objective: To evaluate dermatoglyphics as a noninvasive anatomical marker of carcinoma breast. To find patterns most commonly associated with carcinoma breast.
Results and Conclusions: Presence of an ulnar or radial whorl or an arch on six or more than six fingertips coupled with absence of a radial loop and central whorl is strongly associated with carcinoma breast. The most common pattern found in cases (49.70%) as well as controls (64.40%) was Ulnar loop (X2= 18.94, p< 0.001). Stastically significant decreased intensity of ulnar loops in patients with carcinoma breast was compensated by stastically significant increased intensity of ulnar whorls (26.90%) radial whorls (6.90%), Arches (7.4%). Fingertips of controls showed stastically significant increased frequency of central whorl
(10%) Radial loops (3.2%).
Keywords: Digital dermatoglyphics, Carcinoma Breast, Loops, Arches, Whorls
Citation:
Vaishali Paranjape, Ashwini Kundalkar, P. Vatsala Swamy, Yashwant Kulkarni. DIGITAL DERMATOGLYPHICS IN CARCINOMA BREAST International Journal of Current Research and Review. 7(21), November, 47-52
References:
1. ICMR Bulletin Estrogens and breast cancer. 2003 Feb; 3(2): 13-24.
2. Cotran, Kumar, Robins: Robins Pathologic Basis of Disease. 4th Edition, W.B. Sunders International edition. 1192-1193.
3. Hulka, B.S. and Stark, A.T. Breast cancer: cause and prevention. Lancet. 1995; 346: 833.
4. Kelsey, J.L. Gammon, M.D. and Jhon, E.M. Reproductive Factors and Breast Cancer. Epidemiol Rev. 1933; 15:36.
5. Kuller, L.H. Eating fat or being fat and risk of cardiovascular disease and cancer among women. Ann Epidemiol. 1994; 4:199.
6. Wu, A.H. Pike, M.C. and Starm, D.O. Meta analysis: dietary fat intake, serum estrogens levels, and the risk of breast cancer. J Natl Cancer Inst. 1999; 91:529.
7. Miller, W.R. Estrogen and breast cancer: Biological considerations. Br Med Bull. 1990; 47: 470. 8. Robert L. Nussbaum, Roderick R. McInnes, Hungtington F. Willard, Thompson and Thompson Genetics in Medicine. 6th Edition. Genetics and Cancer. pp. 311-333.
9. Fuller, I.CInherited. Predisposition to cancer. British J of ca. 1973; 28:186.
10. Ciovirnache. M, Dumitru. L, Mogos. I, Spandonide. T, Damian. A, Handoca. A, Stoenescu. D, Dermatoglyphics in thyroid cancer. Endocrinologie. 1986; 24(3): 171-83.
11. Edelstein, J. Amylon,M. Walsh, J.A. Dermsatoglyphics and acute lymphocytic lukemia in children. Pediar Oncol Nur. 1991; 8(1):30-8.
12. Murray H. Seltzer, Chris C. Plato, Peter E. Engler, and H. Stephen Fletcher. Digital dermatoglyphics and breast cancer.Berast cancer research and treatment.1982; 2,261-265.
13. Seltzer, M.H. Plato, C.C. Fox, K.M. Dermatoglyphics in the identification of women either with or at risk for breast cancer. Am J Med Genet. 1990; 37(4):482-8.
14. Abilasha S, Harisudha R, Janaki CS. Dermatoglyphics: a predictor tool to analyze the occurrence of breast cancer. Int J Med Res Health Sci. 2014;3(1): 28-13.
15. Bhanu B. V. (1991).Digital patterns: A new classification system in dermatoglyphics today. B Mohan Reddy, S.B. Reddy, S.B. Roy, and B.N. Sarkar. (eds) Calcutta: 1-16.
16. Sakineh Abbasi, Nahid Einollahi, Nasrin Dashti, F. Vaez-Zadeh. Study of dermatoglyphic patterns of hands in women with breast cancer. Pak J Med Sci 2006 ; (22) 1 : 19-22.
17. Chintamani , Rohan Khandelwal, Aliza Mittal, Sai Saijanani. Amita Tuteja, Anju Bansal, Dinesh Bhatnagar and Sunita Saxena. Qualitative and quantitative dermatoglyphic traits in patients with breast cancer: a prospective clinical study. BMC Cancer 2007; 7:44.
18. J Lavannya, P Saraswathi, J Vijayakumar, S Prathap. Analysis of dermatoglyphc traits in patients with breast cancer. Journal of Pharmaceutical and Biomedical Sciences. 2012; 23(24): 1-5.
19. Aprajita Raizada, Vishwas Johri, T Ramnath, D S Chowdhary, R P Garg. A Cross-Sectional Study on the Palmar Dermatoglyphics in Relation to Carcinoma Breast Patients. Journal of Clinical and Diagnostic Research. 2013 April, 7(4): 609-612.
20. S.B. Sukre, A.A. Mahajan, A.G. Shroff. (2003) Dermatoglyphics in the identification of women either with or at risk for breast cancer. Paper presented at National Conference Anatomical Society Of India Dec 2003; Smt N. H. L. M. Medical College Ahmedabad.
21. P.E. Natekar, F. M. DeSouza, D.D. Motghare and A.K. Pandey. Digital Dermal Patterns in Carcinoma of Breast. Anthropologist .2006; 8(4): 251-254.
22. Oladipo GS, Paul CW, Bob-Manuel IF, Fawehinmi HB, Edibamode EI. Study of digital and palmar dermatoglyphic patterns of Nigerian women with malignant mammary neoplasm. J. Appl. Biosci.2009; 15: 829-34.
23. Daljit Singh, B.R.Prabhakar, Shivmohan Singh Bhalla Dermatoglyphic study in breast carcinoma. Indian J. Pathol Microbiol. 1979; 21: 27-32.
24. Nandy A. Identification of an individual In: Principles of Forensic Medicine. New Central Book Agency (P) Ltd. Calcutta. 2nd ed. (Reprint); 2001: 48- 111.
25. Uduak Umana, C.O. Ahunna, J.A. Timbuak, A.O. Ibegbu, S.A. Musa and W.O. Hamman. Dermatoglyphics and Cheiloscopic Patterns in Cancer Patients; A Study in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria. Current Research Journal of Biological Sciences. 2013; 5(5): 220-225.
|