IJCRR - Vol 07 Issue 21, November, 2015
DIGITAL DERMATOGLYPHICS IN CARCINOMA BREAST
Author: Vaishali Paranjape, Ashwini Kundalkar, P. Vatsala Swamy, Yashwant Kulkarni
Carcinoma breast is the second most common cancer amongst Indian women. Environmental factors, abnormal genetic background, mutations, hormones and changing lifestyle along with genes 17q21: BRCA1 and 13q21:BRCA2 have strong impact on in its etiopathogenesis. Dermatoglyphic patterns are determined by multiple genes and has multifactorial inheritance. Patterns are unique for every individual, remain unaltered throughout life, easy to record and can be studied by non invasive techniques.
Methods: Digital dermatoglyphics of 100 histopathologically proven cases of Carcinoma breast were recorded, classified and compared with dermatoglypic patterns of 100 subjects not suffering from any clinically obvious genetic disease.
Objective: To evaluate dermatoglyphics as a noninvasive anatomical marker of carcinoma breast. To find patterns most commonly associated with carcinoma breast.
Results and Conclusions: Presence of an ulnar or radial whorl or an arch on six or more than six fingertips coupled with absence of a radial loop and central whorl is strongly associated with carcinoma breast. The most common pattern found in cases (49.70%) as well as controls (64.40%) was Ulnar loop (X2= 18.94, p< 0.001). Stastically significant decreased intensity of ulnar loops in patients with carcinoma breast was compensated by stastically significant increased intensity of ulnar whorls (26.90%) radial whorls (6.90%), Arches (7.4%). Fingertips of controls showed stastically significant increased frequency of central whorl
(10%) Radial loops (3.2%).
Keywords: Digital dermatoglyphics, Carcinoma Breast, Loops, Arches, Whorls
Vaishali Paranjape, Ashwini Kundalkar, P. Vatsala Swamy, Yashwant Kulkarni. DIGITAL DERMATOGLYPHICS IN CARCINOMA BREAST International Journal of Current Research and Review. Vol 07 Issue 21, November, 47-52
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