IJCRR - Vol 07 Issue 22, November, 2015
CLINICOPATHOLOGICAL STUDY OF ENDOMETRIUM IN PATIENTS WITH ABNORMAL UTERINE BLEEDING
Author: Humaira Bashir, Nazia Bhat, Mehnaz Sultan Khuroo, Ruby Reshi, Mir Junaid Nazeir, Mohammad Zubair Qureshi
Objectives: Abnormal Uterine Bleeding (AUB) is considered one of the most common and challenging problems presenting to the gynaecologist, regardless of the age the women .The present study was done with the aim of studying the histopathological pattern of the endometrium in women of various age groups presenting with abnormal uterine bleeding.
Methods: This was a prospective study conducted on endometrial curettings of 460 patients in the Department of Pathology, from January 2013 to August 2014.
Results: The age of patients ranged from 18 to 70 yrs. The patients were categorized in reproductive age group (<40yrs), perimenopausal >40yrs and post-menopausal group (>50yrs/clinical scenario). Maximum number of patients were in the perimenopausal group, 220 patients (47.8%), followed by 182 patients (39.6%) in the reproductive age group. Post-menopausal patients constituted 12.6 % ( 58) of total no of cases. Menorrhagia was the most common presenting symptom. Normal cyclic endometrium, 210 cases (45.65%), was the most common histopathological pattern seen in the reproductive and perimenopausal group,
whereas in the postmenopausal group simple hyperplasia, 16 cases (27.6%), followed by complex hyperplasia, 8 cases (13.7%) was the commonest pattern seen. Malignancy was seen in 7 cases (1.52%)
Conclusion: Histopathological examination of endometrial curetting specimens in patients with Abnormal uterine bleeding showed a wide spectrum of histopathological changes ranging from normal endometrium on one hand to malignancy on another hand thus rendering endometrial curetting an important diagnostic procedure in evaluation of Abnormal uterine bleeding. Accurate analysis of endometrial samplings is the key to effective therapy and optimal outcome
Keywords: Abnormal uterine bleeding, Endometrial hyperplasia, Histopathology
Humaira Bashir, Nazia Bhat, Mehnaz Sultan Khuroo, Ruby Reshi, Mir Junaid Nazeir, Mohammad Zubair Qureshi. CLINICOPATHOLOGICAL STUDY OF ENDOMETRIUM IN PATIENTS WITH ABNORMAL UTERINE BLEEDING International Journal of Current Research and Review. Vol 07 Issue 22, November, 67-73
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