IJCRR - 7(23), December, 2015
LIPID PROFILE AND RISK OF OBESITY AMONG URBAN ADULTS
Author: Surinder Sharma, Bhuwan Sharma
Background: Dyslipidemia is a major risk factor for coronary heart disease and refers to lipid abnormalities such as high total cholesterol (TC), elevated low density lipoprotein cholesterol (LDL-C), hypertriglyceridemia, low high density lipoprotein cholesterol (HDL-C).Due to the scarcity of data, we performed a descriptive study so as to understand the pattern of lipid profile in an urban city in North India and the risk of obesity running in them.
Methods: This cross-sectional study was performed by collecting data from three private hospitals in the city from January 1, 2014 till June 31, 2014. Patients who satisfied our inclusion criteria were included in the study. Participants of the study underwent standard hematological testing along with variables about their past medical history and anthropometric measurements were taken. Data was analyzed using SPSS version 21.
Results: 636 patients were included in the study. 54% of the patients were males, 64% less than 65 years of age, 35% were overweight and 16% were obese. 33% were taking some form of lipid lowering drug. 67% had TC < 200 mg%, LDL-C < 130 mg% and HDL-C > 40 mg%. TC, LDL-C and triglycerides were found to be significantly associated with age and body mass index of the patient.
Conclusion: This was the first study in the region to look at the baseline lipid profile of patients. Assessing dietary habits, nutritional status of patients, genetic make up and environmental factors and correlating that with their lipid profile variables would be the next step and would constitute areas of future research.
Keywords: Lipid, Population, Obesity, Dietary, Prevention, Urban
Surinder Sharma, Bhuwan Sharma. LIPID PROFILE AND RISK OF OBESITY AMONG URBAN ADULTS International Journal of Current Research and Review. 7(23), December, 30-33
1. WHO mortality database. Website http://www.who.int/healthinfo/mortality_data/en/ Accessed Oct 15, 2015.
2. Bao W, Srinivasan SR, Wattigney WA and Berenson GS (1995): The relation of parental cardiovascular disease to risk factors in children and young adults. The Bogalusa Heart Study.Circulation 91, 365–371.
3. Shaw LW (1981): Effects of a prescribed supervised exercise program on mortality and cardiovascular morbidity in patients after myocardial infarction. The National Exercise and Heart Disease Project. Am. J. Cardiol. 48, 39–46.
4. World Health Organization. Quantifying selected major risks to health. In: The World Health Report 2002 - Reducing Risks, Promoting Healthy Life. Ch. 4. Geneva: World Health Organization; 2002. p. 47-97.
5. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-97.
6. Bhopal, R., N. Unwin, M. White, J. Yallop, L. Walker, K. G. M. M. Alberti, J. Harland, S. Patel, N. Ahmad, C. Turner, B. Watson, D. Kaur, A. Kulkarni, M. Laker, and A. Tavridou. 1999. Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Ban- gladeshi, and European origin populations: cross sectional study. BMJ. 319: 215 – 220.
7. Mahley, R. W., K. Erhan-Palaoglu, Z. Atak, J. Dawson-Pepin, A. M. Langlois, V. Cheung, H. Onat, P. Fulks, L. Mahley, F. Vakar, S. O?zbayrakci, O. Go?kdemir, and W. Winkler. 1995. Turkish heart study: lipids, lipoproteins and apolipoproteins. J. Lipid Res. 36: 839 – 859.
8. Zavaroni I, Dall’Aglio E, Alpi O, Bruschi F, Bonora E, Pezzarossa A, et al. Evidence for an independent relationship between plasma insulin and concentration of high density lipoprotein cholesterol and triglyceride. Atherosclerosis 1985;55:259-66.
9. Park H, Kim K. Association of alcohol consumption with lipid profile in hypertensive men. Alcohol Alcohol 2012;47:282-7.