A DRUG UTILIZATION STUDY OF FIXED DOSE COMBINATIONS USED IN HYPERTENSION IN RURAL TERTIARY HEALTH CARE CENTRE OF CENTRAL INDIA

Shende T.R.; Siddiqui R.A.; Mahajan H.M.

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IJCRR - 8(12), June, 2016

Pages: 30-34

A DRUG UTILIZATION STUDY OF FIXED DOSE COMBINATIONS USED IN HYPERTENSION IN RURAL TERTIARY HEALTH CARE CENTRE OF CENTRAL INDIA

Author: Shende T.R., Siddiqui R.A., Mahajan H.M.

Category: Healthcare

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Abstract:

Hypertension (HTN) accounts for 7.6 million deaths (13–15% of the total) worldwide. The efficacy of antihypertensive agents in lowering blood pressure (BP) and complications of hypertension is well documented. For prime control of BP, two or more antihypertensive agents are required by large number of patients. Aims and Objectives: To analyze the pattern of fixed dose combinations (FDCs) prescribed for treatment of hypertension and blood pressure `control in patients who came to Medicine department of a tertiary care hospital of central India, to get a better perspective in the fallacies and implement improvements to overcome them for better management of hypertension. Material and Methods: The present study was a cross-sectional retrospective record based observational study conducted at Medicine Department of NKP Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital, Nagpur (M.S.). Results: Out of total 164 case records analyzed, 94 (57.3%) were males and 70 (42.6%) were females. Maximum patients belonged to age group >50 years-64 (39%). FDCs were prescribed in 70 patients out of 164 (42.6%), out of which 2 drug FDCs was used most commonly. Overall most commonly prescribed FDC was that of beta blocker (BB) + calcium channel blocker (CCB) used in 23 patients (32.8%), amongst which metoprolol + amlodipine was most commonly prescribed. Conclusion: In the present study physicians preferred monotherapy over FDCs. Such studies should be conducted on timely basis to detect emerging trends in treatment of hypertension, so that health care policies can be planned accordingly.

Keywords: Fixed dose combinations, Antihypertensive agents

Citation:

Shende T.R., Siddiqui R.A., Mahajan H.M.. A DRUG UTILIZATION STUDY OF FIXED DOSE COMBINATIONS USED IN HYPERTENSION IN RURAL TERTIARY HEALTH CARE CENTRE OF CENTRAL INDIA International Journal of Current Research and Review. 8(12), June, 30-34

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