IJCRR - 8(23), December, 2016
CEREBRAL ASYMMETRY: A CADAVERIC STUDY
Author: Archana Rani, Rakesh Kumar Verma, Arvind Kumar Pankaj, Rakesh Kumar Diwan, Anita Rani, Deepshikha Kori
Objectives: Anatomical brain asymmetries in cadaveric human brains are not well defined in the literature. Therefore, the present study was undertaken to observe the variations in right and left cerebral hemispheres using various parameters.
Methods: Twenty eight adult human brains irrespective of sex were taken for the present study. Various measurements of cerebral hemisphere including fronto-occipital length, cerebral width, Sylvian fissure length and distance between anterior Sylvian point to inferior Rolandic point were taken. These measurements were taken by Vernier calipers. Different configuration of the anterior ascending and anterior horizontal ramus of the Sylvian fissure were also examined as U-shaped, V-shaped and Y-shaped. The presence or absence of triangular sulcus located within pars triangularis was also observed.
Results: The fronto-occipital length was longer on right side while the cerebral width and Sylvian fissure length were more on left side. These values were significant statistically.
The configuration of the anterior ascending and anterior horizontal ramus of the Sylvian fissure was V-shaped in maximum number of hemispheres followed by U-shaped. The triangular sulcus was noted in thirty hemispheres i.e. 16 right and 14 left.
Conclusions: Hemispheres of the brain are not identical and functional asymmetries have an underlying anatomical basis.
Keywords: Cerebrum, Morphometry, Sylvian fissure, Triangular sulcus
Archana Rani, Rakesh Kumar Verma, Arvind Kumar Pankaj, Rakesh Kumar Diwan, Anita Rani, Deepshikha Kori. CEREBRAL ASYMMETRY: A CADAVERIC STUDY International Journal of Current Research and Review. 8(23), December, 21-25
1. Mancall EL, Brock DG.Gray’s Clinical Neuroanatomy. The Anatomical Basis for Clinical Neuroscience. Elsevier Saunders Philadelphia, 1st ed., 2011; 308-11.
2. Knaus TA, Corey DM, Bollich AM, Lemen LC, Foundas AL. Anatomical asymmetries of anterior perisylvian speech-language regions. Cortex. 2007;43:499–510.
3. Greve DN, Van der Haegen L, Cai Q, Stuffle beam S, Sabuncu MR, Fischl B, et al. A surface-based analysis of language lateralization and cortical asymmetry. J Cogn Neurosci. 2013;25:1477– 92.
4. Petrides M. Neuroanatomy of Language Regions of the Human Brain. 1sted, In: Morphological features of the core language regions: The Sulci and Gyri. Amsterdam, Boston: Elsevier, 2013: 21-22.
5. Toga AW, Thompson PM. Mapping Brain Asymmetry. Nat. Rev. Neurosci. 2003; 4: 37.
6. Markow TA, Martin JF. Inbreeding and developmental stability in a small human-population. Annals of Human Biology. 1993; 20: 389-94.
7. Mellor C. Dermatoglyphic evidence of fluctuating asymmetry in schizophrenia. Br Jpsychiatry. 1992;160: 467–72.
8. Burton C, Stevenson JC, Williams DC, Everson PM, Mahoney ER. Attention DeficitDisorder (ADD) and fluctuating asymmetry (FA) in a college sample. Am. J. Hum. Biol. 2002; 14: 7.
9. Burton C, Stevenson JC, Williams DC, Everson PM, Mahoney ER, Trimble JE. Attention deficit hyperactivity disorder (AD/ HD) and fluctuating asymmetry in a college sample: An exploratory study. Am. J. Hum. Biol. 2003; 15: 601–19.
10. Naugler CT, Ludman MD. Fluctuating asymmetry and disorders of developmental origins. Am. J. Med. Genet. 1996; 66: 15–20.
11. Barden HS. Fluctuating dental asymmetry: A measure of developmental instability in Down syndrome. Am. J. Phys. Anthropol. 1980; 52: 169–73.
12. Galaburda AM, Rosen GD, Sherman GF. Individual variability in cortical organization: its relationship to brain laterality and implications to function. Neuropsychologia. 1990; 28: 529– 46.
13. Chi JG, Dooling EC, Gilles FH. Gyral development of the human brain. Annals of Neurology. 1977; 1 (1): 86-93.
14. Eberstaller O, Das Stimhim. Ein Beitragzur Anatomie der oberflache des Gehirns. Urban and Schwarzenberg, Vienna, Austria, 1890.
15. Cunningham DJ. Contribution to the surface anatomy of the cerebral hemispheres. Dublin, Royal Irish Academy, 1892.
16. Rubens AB, Mahowald MW, Hutton JT. Asymmetry of the lateral (sylvian) fissures in man. Neurology. 1976; 26: 620-24.
17. Boni RC, Prodoscimi FC, Bonsi AB, Almeida TM, Ribeiro LAM. Asymmetries ofthe left and right temporal lobes. Int. J. Morphol. 2007; 25(1):117-20.
18. Foundas AL, Faulhaber JR, Kulynych JJ, Browning CA, Weinberger DR. Hemispheric and sex-linked differences in Sylvian fissure morphology: a quantitative approach using volumetric magnetic resonance imaging. Neuropsychiatry Neuropsychol Behav Neurol. 1999; 12 (1):1–10.
19. Idowu OE, Soyemi S, Atobatele K. Morphometry, asymmetry and variations of the Sylvian fissure and sulci bordering and within the pars triangularis and pars opercularis: An autopsy study. J Clin Diagn Res 2014;8(11): AC11-AC14.
20. Chakrabarti S, Vijayalakshmi S. Interhemispheric variation of Sylvian fissure: A Cadaveric brain study. Int J Anat Res. 2015;3(2):1143-48.
21. Ono M, Kubik S, Abernathy CD. Atlas of the cerebral sulci. New York: Georg Thieme Verlag. 1990; 62-74.
22. Ayberk G, Yagli OE, Comert A, Esmer AF, Canturk N, Tekdemir I, et al. Anatomic relationship between the anterior sylvian point and the pars triangularis. Clin. Anat. 2012;25:429–36.
23. Galaburda AM, LeMay M, Kemper TL, Geschwind N. Rightleft asymmetrics in the brain.Science.1978; 199(4331): 852-6.
24. Rumeau C, Tzourio N, Murayama N, Peretti-Viton P, Levrier O, Joliot M, et al. Location of hand function in the sensorimotor cortex: MR and functional correlation. Am J Neuroradiol. 1994; 15:567–72.
25. Sanes JN, Donoghue JP, Thangaraj V, Edelman RR, Warach S. Shared neural substrates controlling hand movements in human motor cortex. Science. 1995; 268:1775–77.