IJCRR - 5(2), January, 2013
RISK FACTORS FOR BREAST CARCINOMA: A CASE CONTROL STUDY, CENTRAL INDIA
Author: Namrata Thakur, Arun Humne
Background: The upward trend in breast cancer globally and in India has become a matter of great concern. Breast cancer is the most common site-specific cancer in women. Geographical variations in incidence and mortality rates of breast cancer suggest the known risk factors for breast cancer may vary in different parts of the world and that environmental factors are of greater importance than genetic factors. It is important to identify these factors in order to bring down the incidence, morbidity and mortality due to this disease.
Aim: To study some risk factors associated with breast carcinoma and to assess their strength of association. Setting,
Design and Period: This was a case control study carried out in Government Medical College, Nagpur from August 2010 to February 2011. Material and Methods: we have studied 240 women which included 120 histopathologically confirmed cases of breast carcinoma and 120 age (?5 years) and residence (rural / urban) matched controls. The risk factors studied were religion, education, socioeconomic status, diet, marital status, age at marriage, age at menarche, parity, age at first childbirth, duration of breastfeeding, use of oral contraceptive pills, age at menopause, duration of reproductive life, hormone replacement therapy, exposure to radiation, previous benign breast condition, family history and time since initiation of breastfeeding after delivery.
Results and conclusion: After adjusting with known risk factors, the strongest risk was observed in women having past H/O breast condition followed by Bouddha religion, age at menarche < 14 years, cumulative duration of breastfeeding ? 36 months, upper socioeconomic status and duration of reproductive life > 30 years.
Keywords: breast carcinoma, risk factors, case control, India.
Namrata Thakur, Arun Humne. RISK FACTORS FOR BREAST CARCINOMA: A CASE CONTROL STUDY, CENTRAL INDIA International Journal of Current Research and Review. 5(2), January, 83-93
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