PHYTOCHEMISTRY, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF MEDICINAL PLANTS- A COMPARATIVE STUDY

Rajamurugan R.; Deepa V.; Sivashanmugam M.; Raghavan C. M.

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IJCRR - 5(2), January, 2013

Pages: 08-19

PHYTOCHEMISTRY, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF MEDICINAL PLANTS- A COMPARATIVE STUDY

Author: Rajamurugan R., Deepa V., Sivashanmugam M., Raghavan C. M.

Category: General Sciences

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Abstract:

Plants are the most important sources of medicines. Today the large number of drugs in use is derived from plants. The important advantages for therapeutic uses of medicinal plants in various ailments are their safety besides being economical, effective and easy availability. The present investigation was aimed to screen phytochemicals, antioxidant and antibacterial activities of ethanolic extracts of leaves of Aegle marmelos, Ocimum sanctum, Alternanthera sessilis, Eclipta alba, and Acalypha indica. The phytochemical analysis revealed the presence of terpenoids, phenols, flavonoids, tannins, alkaloids, cardiac glycosides, and steroids in all the extracts. The antioxidant activity of the extracts was evaluated by DPPH, ABTS and reducing power assay. All the extracts showed significant antioxidant activity. The plant preparations were also screened individually for antibacterial activity against three selected bacterial sp by agar-well diffusion method. Results showed that all the extracts were effective against bacterial sp tested.

Keywords: Aegle marmelos, Ocimum sanctum, Alternanthera sessilis, Antioxidant activity, Antimicrobial activity.

Citation:

Rajamurugan R., Deepa V., Sivashanmugam M., Raghavan C. M.. PHYTOCHEMISTRY, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF MEDICINAL PLANTS- A COMPARATIVE STUDY International Journal of Current Research and Review. 5(2), January, 08-19

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Fig. 2. Scavenging activity (%) on ABTS radicals of the extracts. Each value is expressed as mean ± standard deviation (n = 3). Am- Aegle marmelos, Os- Ocimum sanctum, As- Alternanthera sessilis, Ea- Eclipta alba, and AiAcalypha indica; and ASC- Ascorbic acid

Fig. 3. Reducing power of the extracts (higher absorbance indicates higher reducing power). Each value is expressed as mean ± standard deviation (n = 3). Am- Aegle marmelos, Os- Ocimum sanctum, As- Alternanthera sessilis, Ea- Eclipta alba, and AiAcalypha indica; and ASC- Ascorbic acid

Fig.4. Antibacterial activities of the extracts against E. coli (agar-well diffusion method). Am- Aegle marmelos, Os- Ocimum sanctum, As- Alternanthera sessilis, Ea- Eclipta alba, and Ai- Acalypha indica

Fig.5. Antibacterial activities of the extracts against S. aureus (agar-well diffusion method). Am- Aegle marmelos, Os- Ocimum sanctum, As- Alternanthera sessilis, Ea- Eclipta alba, and Ai- Acalypha indica

Fig.6. Antibacterial activities of the extracts against Pr. mirabilis (agar-well diffusion method). AmAegle marmelos, Os- Ocimum sanctum, As- Alternanthera sessilis, Ea- Eclipta alba, and Ai- Acalypha indica.

Fig.7. Antibacterial activities of the extracts (agar-well diffusion method). 7 A- Aegle marmelos, S.aureus; 7 B- Aegle marmelos Pr. mirabilis; 7 C- Aegle marmelos, E. coli; 7 D- Ocimum sanctum, S.aureus; 7 E- Ocimum sanctum, Pr. mirabilis; 7 F- Ocimum sanctum, E. coli; 7 G- Alternanthera sessilis, S.aureus; 7 H- Alternanthera sessilis, Pr. mirabilis; 7 I- Alternanthera sessilis, E. coli; 7 JEclipta alba, S.aureus; 7 K- Eclipta alba, Pr. mirabilis; 7 L- Eclipta alba, E. coli; 7 M- Acalypha indica, S.aureus; and 7 N- Acalypha indica, Pr. mirabilis;7 O- Acalypha indica, E. coli.

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List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

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