IJCRR - 5(10), May, 2013
HISTOPATHOLOGICAL STUDY OF ORAL CAVITY LESIONS: A STUDY ON 100 CASES.
Author: Nikunj V. Mehta, Kalpana K. Dave, R.N.Gonsai, H.M.Goswami, Purvi S. Patel, Tarang B. Kadam
Background: Oral cavity is one of the most common sites for tumours and tumour like lesions in males especially in India. Squamous cell carcinoma is single most common malignant lesion of this region and related to continuous use of tobacco. Aims and objectives: To study the histopathology of different benign and malignant oral lesions and to compare the observed findings to similar studies with relation to age, sex and site distribution. Materials and methods: This was a retrospective study carried out in the Department of Histopathology, B.J.Medical College, Civil Hospital, Ahmedabad from January 2012 to December 2012. A total of 100 cases of oral cavity lesions were studied. Results: Benign lesions were more common than malignant lesions. The most common site was buccal mucosa with 32 cases (32%) followed by lip with 22 cases (22%). Out of the 100 cases, 75 cases (75%) were benign and 25 cases (25%) were malignant. Out of 25 malignant cases, 22 cases (22%) were conventional squamous cell carcinoma and 1 case each of clear cell odontogenic tumour, low grade mucoepidermoid carcinoma and verrucous carcinoma. Conclusion: A higher degree of suspicion, based on clinical findings and associated risk factors, precise histopathological typing of lesions to confirm or rule out malignancy is essential in the management of oral lesions.
Keywords: Oral cavity, Benign, Malignant.
Nikunj V. Mehta, Kalpana K. Dave, R.N.Gonsai, H.M.Goswami, Purvi S. Patel, Tarang B. Kadam. HISTOPATHOLOGICAL STUDY OF ORAL CAVITY LESIONS: A STUDY ON 100 CASES. International Journal of Current Research and Review. 5(10), May, 110-116
1. Shamim T, Varghese VI, Shameena PM,et al. A retrospective analysis of gingival biopsied lesions in south Indian population : 2001- 2006.Med Oral Pathol Oral Cir Buccal 2008; 13: E414-8.
2. Mujica V, Rivera H, Carrero M. Prevelance of oral soft tissue lesions in an elderly Venezuelan population. Med Oral Pathol Oral Cir Bucal 2008;13:E270-4.
3. Al-Khateeb TH. Benign oral masses in a Northern Jordanian population- a retrospective study. Open Dent J 2009;3:147- 53.
4. Pudasaini S, Baral R, Oral cavity lesions: A study of 21 cases, Journal of Pathology of Nepal (2011)Vol.1,49-51.
5. Furlong MA,Fanburg-Smith JC, Childers EL. Lipoma of the oral and maxillofacial region: site and subclassification of 125 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:441-50.
6. Ildstad ST, Bigelow ME, and Remensnyder JP. Squamous cell carcinoma of the alveolar ridge and palate. A 15-year survey. Ann Surg 1984;199:445-53.
7. Weber RS, Peters LJ, Wolf P, Guillamondegui O. Squamous cell carcinoma of the soft palate, uvula, and anterior faucial pillar. Otolaryngol Head Neck Surg 1988;99:16-23.
8. Oliveira DT, Consolaro A, Freitas FJ. Histopathological Spectrum of 112 cases of mucocele. Braz Dent J 1993;4:29-36.
9. Muramatsu T, Hashimoto S,Inoue T,Shimono M,Noma H, Shigenmatsu T : Clear cell odontogenic carcinoma on the mandibleHistochemical and immunohistochemical observation with a review of literature. J Oral Pathol Med 1996;25:516-521.
10. Madhu K. Nair, E. Jefferson Burkes and Onanong Chai-U-Dom: Radiographic manifestation of clear cell odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89: 250-254.
11. B.S.M.S. Siriwardena, W.M. Tilakaratne, R.M.S.K. Rajapaksha : clear cell odontogenic carcinoma- A case report and review of literature. Int J Oral Maxillofac Surg;33;512- 514.
12. Rosai amd ackerman’s, surgical pathology, 3 rd edition, verrucous carcinoma :Chapter 5:246-247.
13. Som PM, Curtin HD. Head and Neck Imaging, Volume 1 und. Mosby. (2003)ISBN:0323009425.