International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 5(3), February, 2013

Pages: 83-91

HISTOPATHOLOGICAL SPECTRUM OF SINONASAL MASSES -A STUDY OF 162 CASES.

Author: Seema K. Modh, K. N. Delwadia, R. N. Gonsai

Category: Healthcare

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Abstract:

Introduction:

Lesions of the sinonasal region are commonly encountered in clinical practice and important from clinical and pathological perspectives as they have a varieties of histological patterns.

Aims and Objectives:

1) To study the incidence of benign and malignant lesions of sinonasal region.

(2) To study distribution of various lesions for sex differences and symptomatology.

(3) To compare the findings of the study with other studies. Methods: Present study included 162 polypoidal lesions of the nasal cavity. The study period constituted from December 2011 to October 2012. All the tissues were fixed in 10% buffered formalin, processed, stained with H and E and studied for various histopathological patterns. Periodic acid Schiff’s and reticulin stains were used wherever necessary. Results: Among 162 cases, 110 cases (67.11%) were nonneoplastic and 52 cases (32.09%) were neoplastic. Among the non-inflammatory lesion, nasal polyp (83.64%) was the commonest lesion followed by fungal infection. Benign tumours (69.23%) were more frequent than malignant tumours (30.77%). Among benign neoplastic lesions, angiofibroma (41.67%) was commonest and hemangioma (19.4%) was the next common lesion. All lesions were common in second and third decades, with male predominance. Malignant lesions were comparatively less to that of benign lesions. Squamous cell carcinoma was most common malignant lesion. Conclusion: Categorizing the sinonasal lesions according to histopathological features into various types, helps us to know the clinical presentation, treatment, clinical outcome and prognosis of the disease, so all polypoidal lesions need histological examination.

Keywords: Nonneoplastic, Neoplastic, Benign, Malignant.

 Citation:

Seema K. Modh, K. N. Delwadia, R. N. Gonsai. HISTOPATHOLOGICAL SPECTRUM OF SINONASAL MASSES -A STUDY OF 162 CASES. International Journal of Current Research and Review. 5(3), February, 83-91

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Inflammatory polyp : Proliferation of tubular glands lined by ciliated, respiratory-type epithelium and goblet cells, without nuclear atypia. The stroma is edematous with inflammatory cells and eosinophils

Mucormycosis. Hyphae are broad, often distorted and frequently appear twisted. Branching is rightangled (arrow) and septae are absent (PAS stain).

Non-keratinizing Squamous cell carcinomashowing many broad, interconnecting bands of neoplastic epithelium without keratinization characterizes this lesion and pleomorphic cells with loss of polarity and marked mitotic activity are present (HandE section)

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Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


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A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
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A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
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A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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