IJCRR - 5(3), February, 2013
Pages: 43-46
COMPARISON OF SEROPOSITIVITY OF HIV, HBV, HCV AND SYPHILIS AND MALARIA IN REPLACEMENT AND VOLUNTARY BLOOD DONORS IN WESTERN INDIA
Author: Chetna Jain, N.C. Mogra, Jhaman Mehta, Rishi Diwan, Gaurav Dalela
Category: Healthcare
[Download PDF]
Abstract:
Objective: This study was conducted to evaluate the seroprevalence of HIV, HBV, HCV, and Syphilis and Malaria among blood donors. The data generated will help the clinicians for judicious use of blood as well as awareness regarding the Transfusion transmitted infections. Research Design Methods: A total of 46,224 blood donors were screened during a period from April 2008 to October 2012, at blood bank, S.R.G. Hospital and Medical College Jhalawar - District, Rajasthan State. Results: Among these 22905 (49.55%) were voluntary donors and 25219 (54.58%) were replacement donors .Seropositivity for Human Immunodeficiency Virus (HIV) was 0.034%, Hepatitis B Virus (HBV) was 1.57%, Hepatitis C Virus (HCV) was 0.04%, Rapid plasma Reagin method (RPR) for syphilis was 0.019% and Malaria was 0.017% respectively. Conclusions: Infections are slightly more common among replacement donors compared to voluntary donors. There was a gradual decrease of Transfusion Transmitted Infections (TTIs) in blood donors over the years by reason of following of stringent blood donor selection criteria.
Keywords: Transfusion Transmitted Infections (TTI), Seroprevalence, Human Immunodeficiency Virus (HIV), Hepatitis C Virus (HCV), Hepatitis B Virus (HBV).
Citation:
Chetna Jain, N.C. Mogra, Jhaman Mehta, Rishi Diwan, Gaurav Dalela. COMPARISON OF SEROPOSITIVITY OF HIV, HBV, HCV AND SYPHILIS AND MALARIA IN REPLACEMENT AND VOLUNTARY BLOOD DONORS IN WESTERN INDIA International Journal of Current Research and Review. 5(3), February, 43-46
References:
1. Widman FK (ed) (1985) Technical manual American Association of blood Banks, Arlington, PP 325-344.
2. Jasmin Jasani, Vaidehi Patel, Kaushik Bhuva, Anand Vachhavi. Seroprevalence of transfusion transmissible infections among blood donors in a tertiary care hospital. International Journal of Biological and Medical Research. 2012; 3(1) : 1423-1425, www.biomedscidirect.com.
3. World Health Organization (WHO). Blood safety strategy for African region. Brazzaville, World Health Organization, Regional office for Africa, Brazzaville 2007 : 1-25.
4. Srikrishna A, Sitalaxmi S, Prema Damodar S (1999) How safe are our donors? Indian J. Pathol Microbiol 42: 411-416.
5. Government of India. Drugs and Cosmetics rules, 1945 (Amended in 2009) awailable http://www.cdsco.nic.in/html/drugandcosmetics Act.pdf
6. Gagandeep Kaur, Sabita Basu, Ravneet Kaur; Patterns of infections among blood donors in a tertiary care centre : A retrospective study. TheNational Medical Journal of India Vol 23, No. 3, 2010.
7. Karki’s, Ghimire P, Tiwari BR, 2008. Trends in hepatitis B and hepatitis C seroprevalence among Nepalese blood donors. Indian Journal of Infectious Diseases, 61 : 324-326
8. Dawson G.J., er al. The Journal of the Infectious Diseases, (1988) 157 (1); 149 “Reliable Detection of Individuals Seropositive for the Human Immunodeficiency Virus (HIV) by competitive Immunoassays using Escherichia coli-Expressed HIV structural Protenis.”
9. A.Boniolo M. Dovis, R. Matteja The use of an enzyme linked immunosorbent for screening hybridoma antibodies against Hepatitis B Surface antigen. J. Immunol Meth, 49:1 (1982)
10. Sarin, S.K. and Hess. G. (1998). Transfusion associated Hepatitis, CBS Publishers, New Delhi.
11. Caumes E., Janier M. Syphilis, editions techniques. Encyclo. Med Chir (Paris France) Maladies infectiouses. 8-039-A-10(1994)
12. Garg S, Mathur D.R., Garg D.K., Comparison of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in Western India. Indian J Pathol microbial 2001, 44-409-12.
13. National AIDS Control Organization (NACO) website 2012 http://www.nacoonline.org/upload/Final%20pu blications/Blood%20safety/voluntary%20blood %20donation.pdf
14. Nanda A, Tyagi S, Basu S, Marwah N. Prevalence of transfusion transmitted infections among voluntary and replacement donors. Indian J hemat Blood Transf 2001; 19: 104-5.
15. Sharma RR, Cheema R, Vajapayee M, Raou, Kumar S, Marwaha N, et al. prevalence of markers of transfusion transmissible diseases in voluntary and replacement blood donors. Nat Med J India 2004 ; 17 : 19-21.
16. Chandra T, Kumar A, Gupta A. Prevalence of transfusion transmitted infections in blood donors: An Indian experience. Transfusion 2009; 49(10):2214-20.
17. Chaudhary N, Phadke S (2001) Transfusion transmitted disease. India J Paediatr 68; 951- 958
|