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International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR DOI Prefix (CrossRef): 10.31782/2231-2196

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Abstract

IJCRR - 5(17), September, 2013

Pages: 10-15

SERUM AMYLASE IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Author: Bindu C. M., Vidya Shankar. P., H. V. Shetty, Deepti Gupta

Category: Healthcare

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Abstract:

Introduction: Chronic kidney disease is a progressive loss in renal function over period of many months or years. There is decline in nephron function and number generally quantitated as reduction in glomerular filtration rate. As the GFR declines there is accumulation of metabolic end products excreted by Kidney. Amylase is one of enzyme that is rapidly excreted by kidney, thus patients in chronic kidney disease have elevated serum pancreatic enzymes. Aims and Objectives: The aim of present study was to determine changes in serum total amylase levels in patients with end stage renal disease on hemodialysis and non dialysed chronic kidney disease patients. Material and Method: Fifty patients with end stage renal disease coming for hemodialysis and fifty non dialysed chronic kidney diseases on outpatient follow up were included in this study. Fifty age and gender matched healthy individuals were included as control group. Blood samples were collected from patients as well as controls and were analysed for amylase, urea and creatinine using a fully automated analyzer. The results were analyzed statistically using student “t” test. Result: Present study has showed that serum total amylase levels were significantly higher in end stage renal disease and chronic kidney disease patients as compared to healthy controls (p value <0.001). Serum total amylase levels was above the upper limit in sixty percent of patient and more than twice of upper limit in ten percent of patients. Conclusion: From our study it was concluded that in end stage renal disease and chronic disease patients, serum total amylase levels was found to be elevated .Serum amylase alone as a diagnostic tool in recognising acute pancreatitis leads to false positive results. Hence interpretation of elevated amylase in chronic kidney patients has to be supported by other laboratory and clinical evidence.

Keywords: End stage renal disease, chronic kidney disease, serum amylase

 Citation:

Bindu C. M., Vidya Shankar. P., H. V. Shetty, Deepti Gupta. SERUM AMYLASE IN PATIENTS WITH CHRONIC KIDNEY DISEASE International Journal of Current Research and Review. 5(17), September, 10-15

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Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

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Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

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List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

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