International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
logo
slider
slider
slider
slider
Bootstrap Slider

Indexed and Abstracted in: Crossref, CAS Abstracts, Publons, Google Scholar, Open J-Gate, ROAD, Indian Citation Index (ICI), ResearchGATE, Ulrich's Periodicals Directory, WorldCat (World's largest network of library content and services)

Search Articles

Track manuscript

Full Html

IJCRR - 6(8), April, 2014

Pages: 63-70

Print Article   Download XML  Download PDF

PURE TONE AUDIOMETRIC EVALUATION IN NON-INSULIN DEPENDENT DIABETIC PATIENTS

Author: S. Vijayasundaram, P. Karthikeyan, V. Nirmal Coumare

Category: Healthcare

Abstract:The prevalence of hearing defects in the Indian population is estimated to be about 6%. The risk factors are age, noise, cardiovascular system disorders, Diabetes mellitus and social factors. Aims: The aims of the study were to find out the prevalence and type of hearing loss among diabetic subjects, to establish if there was a relationship between age, duration, severity and complications of Diabetes to the changes in hearing threshold and to establish if there was a relationship between height, weight, family history, diet, blood pressure, blood group and blood cholesterol. Materials and methods: This study included 100 diabetic patients (NIDDM) and 200normal subjects (controls) in the age group of 30 \? 59 years, and the controls were matched for age and sex. A detailed clinical examination was performed using a diabetic proforma and screened for complications. The diagnosis was established with the help of tuning fork tests and audiometric analysis. Diabetic patients were categorized into groups and subgroups and were analyzed for statistical significance. Results: It was found that diabetics have an increased mean threshold of hearing at higher frequencies than non-diabetics. The type of hearing loss is typically bilateral and symmetrical, involving higher frequencies. The complications of the disease, sex, weight, height, family history, diet, blood pressure, blood group and blood cholesterol had no significant correlation with the type of hearing loss and with mean average hearing threshold. Conclusion: A relationship exists between the hearing impairment in diabetic patients and other aspects of the disease, which include age, duration and control of Diabetes mellitus.

Keywords: Pure tone audiometry, Non-insulin dependent Diabetes mellitus, Hearing loss

Full Text:

INTRODUCTION

Diabetes mellitus is a chronic metabolic disorder with an incidence of 1-2% which is classified as non-insulin-dependent diabetes mellitus or insulindependent diabetes mellitus, which corresponds to the previous labels of adult onset diabetes mellitus (Type II) and juvenile onset diabetes mellitus (Type I). They are suspected to be two separate entities from the pathogenesis, with the non-insulin type probably the result of breakdown of interaction of regulatory mechanisms, while insulin-dependent diabetes mellitus may be related to partial destruction of B cells in the pancreas and may be modified by polygenic (suspected to be a specific HLA antigen) and environmental (thought to be a viral infection) factors. An autoimmune component is thought to be responsible for the destruction of the B cells. Pathologically it constitutes the triad of neuropathy, retinopathy and nephropathy.1 Complications from insulin-dependent diabetes are more commonly microvascular, resulting in small vessel disease of the kidneys, retina and the skin as well as neuropathy, and less commonly, macrovascular. Non-insulin-dependent diabetes is more common in obese and older patients with a strong genetic predisposition. Fewer microvascular complications are seen; there is a higher risk of large vessel atherosclerosis, coronary disease and peripheral vascular disease.2 The literature exhibits many contradictions concerning the correlation between hearing impairment and diabetic manifestations. It is evident that good control and regular surveillance for complications enables the patients to lead a normal life. The typical hearing loss described is a progressive, bilateral. Sensorineural deafness of gradual onset affects predominantly the higher frequencies and older patients. There is a decrease in auditory acuity which is similar to that of presbyacusis, but those affected show a hearing loss greater that that expected at that age.3,4 Worldwide the prevalence of hearing impairment is estimated at about 440 million people. Age is the primary risk factor in the population. Other risk factors include noise, cardiovascular disease, Diabetes mellitus and social factors. Non-insulin dependent Diabetes mellitus accounts for almost three quarters of all cases of diabetes. Angiopathy and peripheral neuropathy are well recognized complications. It is reasonable to expect these lesions to affect the inner ear leading to hearing impairment.8,9,10 The oculomotor, trochlear and facial nerve palsies seen in diabetic subjects further suggest that besides autonomic and peripheral neuropathy there is definitely some neuroendocrine defect which contributes to central neuropathy.5

MATERIALSAND METHODS

This study was undertaken on patients who attended the outpatient departments of General Medicine and ENT of Mahatma Gandhi Medical College and Research Institute, Pondicherry, over a period of one year. The aims of the study were to find out the prevalence and type of hearing loss among diabetic subjects, to establish if there was a relationship between age, duration, severity and complications of Diabetes to the changes in hearing threshold and to establish if there was a relationship between height, weight, family history, diet, blood pressure, blood group and blood cholesterol.The inclusion criteria were: (i) diagnosis of Diabetes mellitus based on National Diabetic Data Group of the National Institute of Health (NDDG) criteria and (ii) cases receiving anti-diabetic treatment showing even a normal range of blood sugar. The exclusion criteria included: (i) history of congenital deafness in the family, (ii) history of head injury and intake of ototoxic drugs, (iii) history of chronic suppurative otitis media, (iv) history of previous ear surgery and (v) history of acoustic trauma and noise induced hearing loss. In this study, 200 age and sex matched healthy subjects formed the control group (Group I) and were evaluated along with 100 diagnosed cases of Non-Insulin Dependent Diabetes Mellitus (NIDDM) without (Group II) and with complications (Group III) such as peripheral neuropathy, non-healing ulcer, diabetic retinopathy, hypertension, nephropathy, congestive cardiac failure or ischaemic heart disease. All patients included in the study were subjected to a thorough systemic and ENT examination to rule out any organic pathology in the external and middle ear. Tuning fork tests were done using 256 Hz, 512 Hz and 1024 Hz tuning forks. All patients were screened for diabetic retinopathy in the retina clinic by direct and indirect opthalmoscopic examination of the fundus. Audiological evaluation was done by Pure Tone Audiometry (PTA) in the Department of ENT using Arphi Digital model 500 MK III audiometer. Both air and bone conduction were tested. Audiograms were recorded for each patient. Patients were examined by a neurologist to rule out peripheral neuropathy, which was confirmed by nerve conduction study. Biochemical estimation of blood urea and serum creatinine was carried out to rule out nephropathy. The patients were categorized into groups according to age, sex, duration, severity and complications of diabetes. Hearing loss was assessed purely based on tuning fork tests and audiometric readings only. Statistical data was analysed using epidemiological information package developed by WHO. To find out the statistical significance, Kruskal-Wallis H test (equivalent to Chi square test) was used since the observations were normally distributed and a large sample was taken. Mean, standard deviation and ‘p’ value were calculated and tests of significance carried out. The bone/air conduction thresholds were measured for both right and left ears in all patients and taken for each frequency 250 to 8000 Hz. The mean was further categorized according to the group and analysed statistically.

RESULTS

A total of 300 patients were included in the study, of which, 142 were male and 158 were female, with the age ranging from 30 – 59 years. Table I shows the distribution of hearing impairment among the study population. Hearing impairment among the diabetic population is 48% in comparison with non-diabetic population. Diabetes mellitus is the risk factor which contributes four times more risk of hearing loss in comparison with the control population. Table II shows the average hearing threshold for different frequencies for the study population. The mean threshold at each frequency of all control subjects and diabetic patients were calculated, tabulated and compared. The average thresholds in different frequencies were highly significant. The p value is <0.01 both for bone conduction and air conduction in both ears. An average 40% of people were affected by the average threshold in the diabetic group in higher frequencies in both ears, especially in bone conduction. The age distribution of the diabetic cases included in the study is shown in Table III. The age distribution of diabetic patients ranged from 30 to 60 years and included 47 males and 53 females. A statistically significant relationship was established in relation with age and hearing impairment in diabetic patients. Table IV shows the age-wise distribution of the type of hearing impairment while Table V shows the age-wise distribution of average hearing thresholds in different frequencies of the diabetic subjects. 48 out of 100 diabetic patients were found to have hearing impairment, of which, 25 had sensorineural hearing loss, 18 had mixed hearing loss and 5 had conductive hearing loss. Only one ear was affected in 4 patients while both ears were affected in 44 patients. The mean hearing threshold levels in higher frequencies were affected in both ears in diabetic patients. The duration of Diabetes mellitus, type of hearing loss and percentage of hearing loss were analysed and tabulated in Table VI. The number of years as a diabetic significantly affected the average hearing threshold in higher frequencies, especially more in the 10 – 20 years duration group (53.3%), with a P value of <0.05. 8 out of 30 patients in the 10 – 20 years duration group were affected by bilateral high-tone sensorineural hearing loss. The correlation between duration of Diabetes mellitus and the average hearing threshold in different frequencies is shown in Table VII. The mean average threshold in 20 – 30 years duration group in higher frequencies weas increased and statistically significant. The relationship between control of Diabetes mellitus with average hearing threshold and type of hearing loss was tabulated and analysed and is shown in Tables VIII and IX. 25 patients with hearing impairment were found to have poor glycemic control and of these, 12 were found to have sensorineural hearing loss and 13 were found to have mixed hearing loss. The average hearing threshold is calculated by analysis of variance technique. There is marked reduction in hearing threshold from good to moderate in patients with poor control of diabetes, which is highly significant in higher frequencies (P value <0.001 The correlation between complications of Diabetes mellitus and type of hearing loss and average hearing threshold in different frequencies is shown in Table X and Table XI. The patients with no complications had a relatively high threshold in low and high frequencies than those with no complications (speech frequency equal). There was no statistical significant relationship found.

DISCUSSION

In this study, the average hearing thresholds for higher frequencies of 40% of patients in the diabetic group were found to be affected, especially in bone conduction. Similar results were seen in studies carried out by Axelssonet al3 , Taylor et al7 , Costa19, Kurien et al11, Kutty25 , Agarwal1 and Sharma23 . A positive relationship between age and hearing impairment among diabetics was reported by Kutty25, Agarwal1 and Sharma23. In our study, 48% of diabetic patients were found to have hearing impairment and these patients fell in the 40 – 60 years age group, most having sensorineural or mixed type of hearing loss, with both ears being affected in the majority. A positive correlation between duration of diabetes mellitus and hearing loss was reported by Zelenka et al6 , Axelsson et al3 , Tay26 and Sharma23.Kurien et al11 and Cullen et al12 and few other studies20,21,22,27,28 did not find such a relationship. Duration of diabetes mellitus significantly affected the average hearing threshold in higher frequencies, which was found to be especially significant in the 10 – 20 years duration group. Our study showed a marked reduction in hearing thresholds from good to moderate in patients with poor control of diabetes, which was highly significant in higher frequencies. A similar relationship was reported by Agarwal1 and Sharma24.Krocks collaboration study group (1984)13 and other studies14-18 stated that good control of Diabetes mellitus would decrease or postpone the angiopathic changes in the end organs. Axelssonet al4 , Tay26 and Kutty25 found no relationship between severity of the disease and the hearing threshold.Jorgenson5 , Kurien11 , Agarwal1 , Sharma23,24 showed a distinct relationship between diabetic retinopathy, neuropathy and microangiopathy and the hearing threshold. Our study showed no statistical significant relationship between complications of diabetes mellitus and type of hearing loss and average hearing threshold in different frequencies.

CONCLUSION

The study showed that diabetics have an increased mean threshold at higher frequencies in comparison to non-diabetics. Older age groups, longer duration of diabetes and poor control of diabetes showed strong correlation with significant bilateral high frequency hearing impairment as compared to presbyacusis. No statistically significant relationship was found between hearing impairment and complications of diabetes, weight or other parameters.

CONFLICT(S) OF INTEREST:

NONE ACKNOWLEDGEMENT

The authors acknowledge the immense help received from the scholars whose articles are cited and included in references of this manuscript. The authors are also grateful to authors/ editors/ publishers of all those articles, journals and books from where the literature for the article has been reviewed and discussed.

 

 

References:

REFERENCES

1. Agarwal MK. Otorhinolaryngological studies in diabetics. IJO and  HNS 1998;50:116-121.

2. Verma A, Bisht MS, Ahuja GK. Involvement of central nervous system in diabetes mellitus. Journal of Neurology, Neurosurgery and Psychiatry 1984;47:414-416.

3. Axelsson A, Fagerberg SE. Auditory function in diabetics. ActaOtolaryngologica 1968;66:49-64.

4. Axelsson A, Fagerberg SE. Hearing in diabetics. ActaOtolaryngologica 1978;356:1- 23 (supplement).

5. Jorgensen MD, Buch NH. Studies on inner ear functions and cranial nerves in diabetics. ActaOtolaryngologica 1961;53:350-364.

6. Zelenka J, Kozak P. Disorder in the bloodsupply of the inner ear as an early symptom of diabetic angiopathy. JLO 1965;79:314-319.

7. Taylor IG, Irwin J. Some audiological aspects of diabetes mellitus. JLO 1978;92:9-13.

8. Gibbin KP, Davis CG. A hearing survey in diabetes mellitus. Clinical Otolaryngology 1981;6(3):345-350.

9. Robin PE. Deafness and Diabetes (Editorial). Clinical Otology 1981;6:309.

10. Miller JJ, Beck L, Davis A, Jones DE, Thomas AE. Hearing loss in patients with diabetic retinopathy. AJO 1983;4:342-346.

11. Kurien M, Thomas K, Bhanu TS. Hearing thresholds in patients with diabetes mellitus. JLO 1989;103:164-168.

12. Cullen JR, Cinnamond MJ. Hearing loss in diabetics. JLO 1993;107;179-182.

13. KrocsColloboration Study Group. Blood glucose control and the evolution of diabetic retinopathy and albuminuria. NEJM 1984;311:365-376.

14. Olsen S, Noffsinger D. Comparison of one new and three old tests of auditory adaptation. Archives of Otolaryngology 1974;99:94-99.

15. Friedman SA, Schulman RH, Weiss S. Hearing and diabetic neuropathy. Archives of Internal Medicine 1975;135:573-576.

16. Sieger A, White NH,Skinner MW, Spector GJ. Auditory function in children with diabetes mellitus. Annals of Otology, Rhinology and Laryngology 1983;92:237-241.

17. Wilson R, Soeldner JS. The relationship of idiopathic sudden hearing loss to diabetes mellitus. Laryngoscope 1982;92:155-160.

18. Snashall SE. Bakesey audiometry and tone and reflex decay tests in diabetes. Archives of Otolaryngology 1977; 103:342-343.

19. Costa OA. Inner ear pathology in experimental diabetes. Laryngoscope 1967;77:68-75.

20. Virtaniemi J, Laakso M, Nuutien J. Auditory brainstem latencies in type I (IDDM) diabetic patients. AJO 1993;14(6):413-418.

21. Rudolph. Inner ear damage secondary to Diabetes mellitus. Arch Otolaryngol Head Neck Surg 1990;117:635-640.

22. Wackym PA, Linthicum FH. Diabetes mellitus and hearing loss: clinical and histopathological relationship. AJO 1986;7:176-182.

23. Sharma R et al. Brain stem evoked response in patients with diabetes mellitus. IJO 2000;52:223-228.

24. Sharma R. Audiovestibular changes in diabetes mellitus. IJO and HNS 1999;51:40-43.

25. Kutty SR et al. Hearing loss in diabetes mellitus. IJO and HNS 1998;4:131-135.

26. Tay HL, et al. Diabetes mellitus and hearing loss. ClinOtolaryngol 1995;20(2):130-4.

27. Huang YM, Pan CY, Rui G, Cai XH, Yu LM, Chou CY. Study on the hearing impairment in diabetic patients. Chinese Journal of Otorhinolaryngology 1990;25:354-356.

28. Carmen RE, Svihovec DA, Gocka EF, Gay GC, House LR. Audiometric configuration as a reflection of low plasma glucose and diabetes. AJO 1989;10:372-379.

Announcements

Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021


Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


RSS feed

Indexed and Abstracted in


Antiplagiarism Policy: IJCRR strongly condemn and discourage practice of plagiarism. All received manuscripts have to pass through "Plagiarism Detection Software" test before Toto Macau forwarding for peer review. We consider "Plagiarism is a crime"

IJCRR Code of Conduct: To achieve a high standard of publication, we adopt Good Publishing Practices (updated in 2022) which are inspired by guidelines provided by Committee on Publication Ethics (COPE), Open Access Scholarly Publishers Association (OASPA) and International Committee of Medical Journal Editors (ICMJE)

Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.



ABOUT US

International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

Contact

148, IMSR Building, Ayurvedic Layout,
        Near NIT Complex, Sakkardara,
        Nagpur-24, Maharashtra State, India

editor@ijcrr.com

editor.ijcrr@gmail.com


Copyright © 2024 IJCRR. Specialized online journals by ubijournal .Website by Ubitech solutions