International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 4(13), July, 2012

Pages: 114-118

Date of Publication: 18-Jul-2012


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AUTOMATIC MEDICAL IMAGE SEGMENTATION USING SPATIAL FUZZY CLUSTERING METHOD

Author: R.Aishwarya

Category: General Sciences

Abstract:The performance of the set segmentation is subject to appropriate initialization and optimal configuration of controlling parameters, which requires substantial manual intervention. A new fuzzy level set algorithm is proposed in this paper to facilitate medical image segmentation. Moreover fuzzy level set algorithm is enhanced with locally regularized evolution. Such improvements facilitate level set manipulation and lead to more robust segmentation. Performance evaluation of the proposed algorithm was carried on medical images from different modalities .the results confirm its effectiveness for medical image segmentation.

Keywords: Fuzzy logic, Clustering, Image segmentation, Level set method.

Full Text:

INTRODUCTION
Segmentation is defined as partitioning portions of an image. It adds structure to a raw image. In the case of medicine, this can involve identifying which portions of an image is the tumor, or separating white matter from grey matter in a brain scan. Segmentation is a vital aspect of medical imaging. It aids in the visualization of medical data and diagnostics of various dieses. The result of image segmentation is a set of segments that collectively cover the entire image, or a set of contours extracted from the image (see edge detection). Each of the pixels in a region are similar with respect to some characteristic or computed property, such as color, intensity, or texture. Adjacent regions are significantly different with respect to the same characteristic(s). When applied to a stack of images, typical in Medical imaging, the resulting contours after image segmentation can be used to create 3D reconstructions with the help of interpolation algorithms like marching cubes. we will restrict most of our discussion to approaches that generalize the statistical inference beyond first and second moments to entire probability density functions (pdf). From this, segmentation can be reinterpreted as measuring the ?distance? between two distributions via a similarity metric. we relax the assumption of a-priori knowledge, and focus on the accurate segmentation of biological structures or pathologies found in medical imagery. A qualitative comparison between the Bhattacharyya distance and our newly proposed metric is then done to highlight the notion that similarity measures can not be applied equally for image segmentation. In particular situations, one distribution metric may prevail while another measure may be highly dependent on the initialization or statistical information. To the best of our knowledge, a qualitative comparison of segmentation results has not been made.

Digital Image Segmentation
Image segmentation plays an important role in image analysis and computer vision. The goal of image segmentation is partitioning of an image into a set of disjoint regions with uniform and homogeneous attributes such as intensity, color, tone etc. The image segmentation approaches can be divided into four categories; thresholding, clustering, edge detection, and region extraction. In color images, the boundaries between objects are blurred and distorted due to the imaging acquisition process. Furthermore, object definitions are not always crisp and knowledge about the objects in a scene may be vague. Segmentation is a vital aspect of medical imaging. It aids in the visualization of medical data and diagnostics of various dieses. This report presents an implementation of a level set approach for active contour image segmentation. This method is originally developed by Osher and Sethian and then applied to image segmentation by Malladi. No requirements about objects‘ shape and allowance for very flexible topology change are key advantages for this method. Partitional clustering essentially deals with the task of partitioning a set of entities into a number of homogeneous clusters, with respect to a suitable similarity measure. Due to the fuzzy nature of many practical problems, a number of fuzzy clustering methods have been developed following the general fuzzy set theory strategies outlined by Zadeh, The main difference between the traditional hard clustering and fuzzy clustering can be stated as follows. While in hard clustering an entity belongs only to one cluster, in fuzzy clustering entities are allowed to belong to many clusters with discerent degrees of membership.

Partitional clustering essentially deals with the task of partitioning a set of entities into a number of homogeneous clusters, with respect to the fuzzy cluster structure relates to the data from which it is derived, from this different clusters and shapes can be identified. The data is generated from a cluster structure identified. Image segmentation plays an important role in image analysis and computer vision. The goal of image segmentation is partitioning of an image into a set of disjoint regions with uniform and homogeneous attributes such as intensity, color, tone etc. The image segmentation approaches can be divided into four categories; thresholding, clustering, edge detection, and region extraction. In color images, the boundaries between objects are blurred and distorted due to the imaging acquisition process. Furthermore, object definitions are not always crisp and knowledge about the objects in a scene may be vague. Fuzzy set theory and Fuzzy logic are ideally suited to deal with such uncertainties. Fuzzy clustering models have proved a particularly promising solution to the color clustering problem. Such unsupervised models can be used with any number of features and clusters. The Fuzzy C means (FCM) algorithm, proposed by Bezdek (1981), is the first and most widely used algorithm in image segmentation because it has robust characteristics for ambiguity and can retain much more information than hard segmentation methods. Clustering The notion of a cluster varies between algorithms and is one of the many decisions to take when choosing the appropriate algorithm for a particular problem. A clustering is essentially a set of such clusters, usually containing all objects in the data set. Additionally, it may specify the relationship of the clusters to each other, At first the terminology of a cluster seems obvious: a group of data objects. However, the clusters found by different algorithms vary significantly in their properties, and understanding these cluster models is key to understanding the differences between the various algorithms. Typical cluster models include: Connectivity models: for example hierarchical clustering builds models based on distance connectivity. Centroid models: for example the k-means algorithm represents each cluster by a single mean vector. Distribution models: clusters are modeled using statistic distributions, such as multivariate normal distributions used by the Expectation-maximization algorithm. Density models: for example DBSCAN and OPTICS defines clusters as connected dense regions in the data space. Subspace models: in Biclustering (also known as Co-clustering or two-mode-clustering), clusters are modeled with both cluster members and relevant attributes. Group models: some algorithms (unfortunately) do not provide a refined model for their results and just provide the grouping information. A hierarchy of clusters embedded in each other. Clusterings can be roughly distinguished in:

hard clustering: each object belongs to a cluster or not soft clustering (also: fuzzy clustering): each object belongs to each cluster to a certain degree (e.g. a likelihood of belonging to the cluster).

Fuzzy Clustering
Clustering is the process of dividing the data into homogenous regions based on the similarity of objects; information that is logically similar physically is stored together, in order to increase the efficiency in the database system and to minimize the number of disk access. The process of clustering is to assign the q feature vectors into K clusters, for each kth cluster Ck is its center. Fuzzy Clustering has been used in many fields like pattern recognition and Fuzzy identification. A variety of Fuzzy clustering methods have been proposed and most of them are based upon distance criteria. The most widely used algorithm is the Fuzzy C-Mean algorithm (FCM), it uses reciprocal distance to compute fuzzy weights. This algorithm has as input a predefined number of clusters, which is the k from its name. Means stands for an average location of all the members of particular cluster and the output is a partitioning of k cluster on a set of objects. The objective of the FCM cluster is to minimize the total weighted mean square error: The FCM allows each feature vector to belong to multiple clusters with various fuzzy membership values . Then the final classification will be according to the maximum weight of the feature vector over all clusters. The detailed algorithm: Input: Vectors of objects, each object represent s dimensions, where v = {v1,v2,……,vn} in our case it will be an image pixels, each pixel has three dimensions RGB, K = number of clusters. Output = a set of K clusters which minimize the sum of distance error. Algorithm steps: (1) Initialize random weight for each pixel, it uses fuzzy weighting with positive weights {Wqk } between [0, 1]. (2) Standardize the initial weights for each qth feature vector over all K clusters via (3) Standardize the weights over k = 1,…,K for each q to obtain Wqk

SIMULATION RESULTS
We test our region-based segmentation model on several images, which further demonstrates the viability and possible advantage of our distribution metric for image segmentation. A common example that is often tested with energy models that discriminate on probability distributions is the zebra image. The goal here is to capture the entire zebra by separating the distributions so as to obtain a bimodal ?Object? with a unimodal background. We note that several segmentation methods have been able to capture this image. However, for the sake of completeness, we show results in Figure 4. Stages of the segmentation are shown along with the corresponding plots of the probability distributions. Segmenting biological structures from medical images is often a challenging task. This is due to the inherent inhomogeneous distribution of a photometric variable as well as the low contrast and noise (as seen in the Kaposi Sarcoma). In the remaining examples, we segment both the corpus callosum and an MRI image of a heart.

CONCLUSION
We introduce a new metric for image segmentation that quantifies the ?distance? between two distributions as the standard deviation of the difference between logarithms of those densities. While several metrics and measures have been proposed for image segmentation, results often vary drastically. Specifically, although separating distributions using the Bhattacharyya distance as a measure has resulted in the successful segmentation on some challenging imagery, in other cases such as the Kaposi Sarcoma, the Bhattacharyya - based algorithm fails to capture the infected portion of the skin while the energy model proposed in this paper results in a successful segmentation. The differing segmentation results can be traced to how the respective metrics penalize perturbations on a manifold of distributions. Thus, a subject of future work is to investigate and clarify how differences in metrics affect segmentation.

References:

1. X. Han, C. Xu and J. Prince, ?A topology preserving level set method for geometric deformable models?, IEEE Trans. Patt. Anal. Mach. Intell., vol. 25, pp. 755-768, 2003.

2. J. Gomes and O. Faugeras, ?Reconciling distance functions and Level Sets?, J. Visiual Communic. and Imag. Representation, vol. 11, pp. 209-223, 2000.

3. R. Malladi, J. A. Sethian, and B. C. Vemuri, ?Shape modeling with front propagation: a level set approach?, IEEE Trans. Patt. Anal. Mach. Intell., vol. 17, pp. 158-175, 1995.

4. T. Georgiou, ?Distances and riemannian metrics for spectral density functions,? IEEE Trans. on Signal Processing (8), pp. 3395– 4003, 2007.

5. B. Vemuri and Y. Chen, ?Joint image registration and segmentation", Geometric Level Set Methods in Imaging, Vision, and Graphics, Springer, pp. 251-269, 2003.

6. Chen Zhang and Shixiong Xia, ? K-means Clustering Algorithm with Improved Initial center,? in Second International Workshop on Knowledge Discovery and Data Mining (WKDD), pp. 790-792, 2009.

7. P. Bradley, U. Fayyad, Refining initial points for k-means clustering, Proceedings 15th International Conf, on Machine Learning, San Francisco, CA, 1998, pp. 91-99.

8. J. Pena, J. Lozano and P. Larranaga, An Empirical comparison of four initialization methods for the k-means algorithm, Pattern Recognition Letters Vol. 20, 1999.

9. S.L.Chiu, Fuzzy model identification based on cluster estimation, Journal of Intelligent and Fuzzy Systems.

10. Kiyotaka Mizutani and Sadaaki Miyamoto, Possibilistic Approach to Kernel- Based Fuzzy c-Means Clustering .

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Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

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Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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